What is Aptensio XR?

Aptensio XR is a stimulant that can be used to treat the symptoms of attention deficit hyperactivity disorder (ADHD) for adults and children ages 6 and up.

How does Aptensio XR work?

It affects the parts of the brain and central nervous system that control hyperactivity and impulses. Aptensio XR is a brand name for the generic drug methylphenidate hydrochloride.

When did the U.S. Food and Drug Administration approve Aptensio XR?

 Aptensio was approved by the U.S. Food and Drug Administration in 2015 for treating attention deficit hyperactivity disorder.

Is there a generic version of Aptensio XR available?

Yes, the generic name for Aptensio XR is methylphenidate hydrochloride extended release and it is available for purchase in the United States.

Are there any major differences between Aptensio XR and other stimulants used to treat ADHD?

There are a lot of similarities between Aptensio XR and other stimulants used to treat ADHD. They are all are habit-forming and classified as Schedule II controlled substances.  Therefore, if you have a history of substance use problems, you should talk to your doctor about this before taking either medication. As far as differences, Aptensio XR starts working within an hour, which takes longer than instant release forms of medication such as Ritalin. Aptensio XR also lasts up to 12 hours. Other medications such as Adderall are available in extended release versions as well, which also last up to 12 hours.

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Can children take Aptensio XR?

Children over the age of 6 may be prescribed the medication for ADHD. They should take the medication in the exact amount prescribed by their doctor. The capsule can also be opened and sprinkled into food or liquid and be just as effective. It’s also important to tell your child’s doctor about other medication complications or past substance use history.

Are there potential interaction issues for people taking Aptensio XR and any other drugs? 

Do not take Aptensio XR if you have taken an MAO inhibitor in the past two weeks, as a dangerous interaction effect could occur. Also do not take the medication if you are allergic to methylphenidate hydrochloride. There are also hundreds of drugs which are known to interact with Aptensio XR in major, moderate, or mild ways, so let your doctor know what other medications you are taking before you begin the medication.

Are there any other medical conditions that would make someone ineligible for Aptension XR Therapy?

Aptensio XR might not be right for you if you have heart problems, high blood pressure, or circulation problem. The drug can also make symptoms of severe anxiety or agitation even worse. Also talk to your doctor if you a history of mental illness such as depression or bipolar disorder, or a history of substance use problems.

What is the typical dose prescribed to someone taking Aptensio XR?

The medication can be prescribed in seven different dosage strengths, ranging from 10mg to 60mg. Dosage typically starts at 10mg and then is increased as recommended by your doctor.

How long does it usually take for Aptensio XR to work?

The medication is designed to 40% of the active ingredient within an hour after taking, and the remaining 60% is released throughout the day. The capsule is designed to deliver a “medication peak” another 8 hours after taking the capsule.

 What are Aptensio XR’s most common side effects?

  • stomach pain
  • decreased appetite
  • insomnia
  • headache.

Major side effects should be reported to your doctor immediately, and can include stroke and heart attack for adults, increased blood pressure, increased heart rate, and circulation problems. You can also report them to the FDA at 1-800-FDA-1088 or online.

Are there any psychiatric side effects associated with Aptensio XR?

People who take Aptensio XR may experience psychotic symptoms such as auditory hallucinations, paranoia, and delusional thinking. The medication can also complicate mental illness conditions already present.

Is it safe for a woman who is pregnant, trying to become pregnant, or nursing, to take Aptensio XR?

There are no controlled studies on human pregnancy and Aptensio XR, therefore researchers do not know whether the drug will harmful to the child. The drug can also be transferred via breast milk in small amounts. Therefore, talk to your doctor if you are pregnant, planning to become pregnant, or are nursing, before you take Aptensio XR.

Can symptoms occur if Aptensio XR is discontinued?

Some patients have reported withdrawal symptoms of extreme fatigue and depression when they abruptly discontinue use of the drug.

If taken in overdose, is Aptensio XR toxic?

An overdose of Aptensio XR could be fatal, so seek immediately help or call the Poison Help Line at 1-800-222-1222 if you overdose. Overdose symptoms can include nausea, vomiting, diarrhea, restlessness, anxiety, agitation, tremors, hyperreflexia, muscle twitching, convulsions, coma, euphoria, confusion, hallucinations, delirium, sweating, flushing, headache, hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, hypotension, and dryness of mucous membranes.

Is Aptensio XR habit-forming?

Like other stimulants, Aptensio XR be habit-forming, as users may develop a tolerance to the drug over time. Make sure that you keep track of the medication, keep it locked in a safe place, and never take more than prescribed. It is illegal to give or sell the medication to others. Talk to your doctor if you have a past history of substance dependence before you begin taking the medication.

How much does Aptensio XR cost?

A 90-capsule supply of 10 mg Aptensio XR tablets costs approximately $628 if paying with cash. The generic version, methylphenidate hydrochloride, can be less expensive.

Are there any disadvantages to Aptensio XR?

Disadvantages include potential side effects such as headaches, gastrointestinal problems, dizziness, and insomnia. Also, because the drug is habit-forming, there is risk for abuse and overdose.


DISCLAIMER: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider.  This article mentions drugs that were FDA-approved and available at the time of publication and may not include all possible drug interactions or all FDA warnings or alerts. The author of this page explicitly does not endorse this drug or any specific treatment method. If you have health questions or concerns about interactions, please check with your physician or go to the FDA site for a comprehensive list of warnings.



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Last Updated: Oct 12, 2019