What is Invega?

Invega is a medication known as an atypical antipsychotic that is used to treat symptoms of schizophrenia.

When did the U.S. Food and Drug Administration (FDA) approve the medication?

Invega was first approved by the FDA in 2006.

Is there a generic version of Invega?

Yes, paliperidone is the generic version of Invega and is available in the United States.

Are there any major differences between Invega and other antipsychotics used to treat Invega?

Invega belongs to the class of medications known as atypical antipsychotics or second generation psychotics. Talk to your doctor about what might work best for you and the costs and benefits of taking the medication. Some people may need to try several different antipsychotics before they find the most effective with the fewest side effects.

Can children take Invega?

The efficacy of Invega for treating teenagers ages 12 to 17 has been established. However, teens taking atypical antipsychotics can be at higher risk for side effects such as weight gain. Talk to your child’s doctor about the risks of using the medication.

Are there potential interaction issues for people taking Invega and any other drugs?

There are hundreds of other drugs which are known to interact with Invega in major, moderate, or mild ways, so let your doctor know what other medications you are taking before you begin taking the medication. Some of these include antidepressants, antibiotics, antipsychotics, cisapride, levodopa, anxiety medications blood pressure medications, heart medications, procainamide, quinidine, sotalol, sedatives, sleep medications, and tranquilizers. Also let your doctor know if you have an allergic reaction to the Invega, Risperdal, or any other medications.

Are there any other medical conditions that would make someone ineligible for Invega therapy?

Talk to your doctor about other medical conditions before you take Invega, such as dementia,

heart issues, seizures, stroke, brain tumor, Parkinson’s disease, diabetes, breast cancer, stomach conditions, inflammatory bowel disease, kidney disease, or liver disease. Also, talk to your doctor if you have a history of substance abuse or any other mental health issues.

What is the typical starting dose that would be prescribed to someone taking Invega?

The recommended dosage for Invega Extended-Release tablets is 6mg taken once daily in the morning. Some patients may benefit from a higher or lower dosage, but a dosage above 12mg daily is not recommended.

What do I do if I miss a dose?

Take the dose of Invega when you remember, but skip the missed dose if it it’s almost time for your next dose. You should never take extra doses of the medication to make up for missed doses.

What common side effects can Invega cause?

Common side effects of Invega can include:

  • Dizziness
  • Dry mouth
  • Weight gain
  • Headaches
  • Extreme fatigue
  • Stomach pain
  • Weakness
  • Increased saliva

Doctors recommend that you not drink alcohol while on the medication. It also is recommended that you wait to drive or operate machinery until you know how the medication affects you. Report major side effects to your doctor immediately, which can include fever, sweating, confusion, irregular or fast heartbeat, muscle pain, restlessness, slow or stiff movements, uncontrollable movement of face or body, and painful erections that last for hours. You can also report side effects to the FDA at 1-800-FDA-1088 or online.

What are the potential long-term effects of taking Invega?

Your doctor should monitor for progression of potential long-term side effect of Invega, which can include weight gain, high blood sugar, high cholesterol, and tardive dyskinesia.

Is it safe for a woman who is pregnant, about to become pregnant, or nursing to take Invega?

There have been no controlled human pregnancy studies on the effects of Invega. The drug may be transferred via human breast milk and potentially harm a baby. Therefore, before taking Invega, talk to your doctor if you are pregnant, planning to become pregnant, or are nursing.

Can symptoms occur if Invega is discontinued?

It’s important not to stop taking the drug if you feel better. Maintain contact with your doctor and seek medical attention if necessary when discontinuing the drug. Talk to your doctor about how to mitigate potential withdrawal symptoms.

What should I do if I overdose on Invega?

Seek immediate help or call the Poison Help Line at 1-800-222-1222 if you overdose, as it can be fatal. Symptoms may include drowsiness, unsteadiness, restlessness, increased heartbeat, slow or stiff movement, and uncontrollable movement of face or body.

Is Invega habit-forming?
Invega has no habit-forming potential, but it is not recommended that you discontinue use of the drug before talking with your doctor, as withdrawal symptoms can occur.

How much does Invega cost?

According to goodrx.com, 30 tablets of 6mg Invega cost approximately $1,000. Thirty tablets of 6mg generic paliperidone cost approximately $800.

Are there any disadvantages to Invega?

The biggest disadvantages of Invega are the potential long-term side effects, which can include tardive dyskinesia, increased blood sugar, increased cholesterol, and weight gain.

DISCLAIMER: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider.  This article mentions drugs that were FDA-approved and available at the time of publication and may not include all possible drug interactions or all FDA warnings or alerts. The author of this page explicitly does not endorse this drug or any specific treatment method. If you have health questions or concerns about interactions, please check with your physician or go to the FDA site for a comprehensive list of warnings.




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Last Updated: Nov 25, 2018